Fructose-10
Fructose BP 10% w/v

Description :
Fructose - 10 is a hypertonic solution, which contains 10 gm fructose in each 100 ml sterile water in PVC bag used as water and nutrient replenisher in diabetic and all other patients.

Uses :
Fructose-10 is used intravenously as a carbohydrate nutrient. It is converted to liver glycogen and metabolized more rapidly than dextrose without requiring insulin and thus may be used in diabetic patients. Fructose-10 is indicated in patients requiring fluid replacement and caloric feeding. It is better “nitrogen-sparer” than glucose.

Dosage and administration :
Dosage depends on age, weight and severity of the disease of the patient, but generally 30-75 drops per minute intravenously or according to physician’s recommendation. The rate of infusion of fructose should not exceed 0.5-1 gm/kg body wt/hr.

Precaution:
Fructose-10 should not be given to patients with hereditary fructose intolerance. It should be given with caution to patients with impaired kidney function or severe liver damage.

Warning :
Infusion of fluid should be immediately discontinued if rigor arises for any reason during the process. Do not use if the solution is cloudy, contains particles, or after expiry date.

Adverse effects :
Intravenous administration of fructose may cause lactic acidosis and hyperuricemia.The rapid infusion of fructose results in facial flushing, abdominal pain and sweating.

Contraindications :
Fructose is contraindicated in certain inborn errors of fructose metabolism, methyl alcohol poisoning, hyperuricemia, liver failure, and lactic acidosis.

Storage :
Fructose-10 should be stored at controlled room temperature

Packaging :
Fructose-10 is available in 500ml & 1000 ml PVC (medical grade) bag containing 10% w/v of fructose BP.